Investigation Of Unexplained Fever featured image

Investigation Of Unexplained Fever

We often see patients with Pyrexia of Unknown Origin (PUO).  Ongoing fever without an obvious source of infection is a diagnostic challenge

Investigation Of Unexplained Fever featured image
6th April 2018
Written by: Dr Gerlis

We often see patients with Pyrexia of Unknown Origin (PUO).  Ongoing fever without an obvious source of infection is a diagnostic challenge.

Having ruled out the common chest, bowel or urine infections, we have run blood and urine tests to look for tropical diseases (eg Dengue Fever or Malaria depending upon travel history) legionella, borrelia (Lyme disease) viral antibodies and inflammatory markers.  We may have found no obvious cause initially but signs of infection ie elevated neutrophil white cell count and ESR/CRP.  The next stage is to run blood cultures and carry out imaging including chest, abdomen and pelvis CT scans plus echocardiography.

We have successfully diagnosed in this way subacute bacterial endocarditis (SBE) which can be treated with a prolonged inpatient course of intravenous antibiotics and in one case heart valve replacement was necessary.  Our work at SameDayDoctor private walk in clinics is often challenging as we endeavour to use all available diagnostic options available to us to make a correct diagnosis and initiate treatment.

Seeking answers to ongoing fever challenges?

SameDayDoctor private GP clinics specialise in diagnostic excellence.

Our dedicated team, experienced in dealing with Pyrexia of Unknown Origin (PUO), employs a thorough diagnostic approach, including tropical disease screenings, blood and urine tests, inflammatory markers, blood cultures, and advanced imaging.

Trust us to unravel the diagnostic puzzle and provide personalised treatment plans. Schedule a consultation with SameDayDoctor's private doctors in London and Manchester. Your health deserves expert attention!