We have had discussions about this exciting new medication. A twice-a-year injection that reduces bad cholesterol to protect the heart is to be pioneered by the NHS in England. Already, millions of people take daily statin pills to cut their cholesterol. But later this year, a “ground-breaking” large-scale clinical trial will offer NHS patients a new form of medicine, gene silencing, in an injection called inclisiran.
Health Secretary Matt Hancock said the initiative could save 30,000 lives during the next decade. By “silencing” the PCSK9 gene, inclisiran can make the liver absorb more “bad” cholesterol from the blood and break it down.
Trials presented at the European Society of Cardiology last year showed it could cut bad cholesterol levels in half within weeks. Prof Kausik Ray, who led those trials, from Imperial College London, says this gives it “enormous” potential. And the Department of Health and Social Care says it would prevent 55,000 heart attacks and strokes each year for every 300,000 patients treated. NHS patients who have not had a heart attack or stroke but are at high risk of having one will be invited to take part in the latest trial. About 40,000 people might be eligible.
Inclisiran will also be assessed for more routine use next year based on evidence from previous trials. At the moment – because of the way decisions on health are devolved within the UK – the announcement applies only in England.
An international team, including researchers from Google Health and Imperial College London, designed and trained a computer model on X-ray images from nearly 29,000 women. AI was still as good as two doctors working together. Unlike humans, AI is tireless. Experts say it could improve detection.
Newly-diagnosed cancer patients are to be offered NHS gym sessions before they start chemotherapy, in the hope of boosting the speed of their recovery. Thousands will be invited to sign up for a “prehab” fitness programme within 48 hours of being diagnosed. The aim is to make patients “match fit” ahead of chemotherapy or major surgery.
Samoa’s main streets are eerily quiet as the government stepped up efforts to curb a measles epidemic that has killed 62 people. The government told most public and private workers to stay home for two days and shut down roads to nonessential vehicles as teams began going door-to-door to administer vaccines. Families in the Pacific island nation were asked to hang red flags from their houses if they needed to be vaccinated.
SameDayDoctor was interviewed by BBC Television regarding the advice to the NHS that swimming is excellent exercise. Furthermore, we conducted a radio interview about a new smear test methodology being trialled.
A life-extending drug for cystic fibrosis will be available on the NHS in England, health bosses say. NHS England reached a deal with Orkambi manufacturers Vertex Pharmaceuticals after months of talks. Patients should be able to get the drug within 30 days. The drug improves lung function and reduces breathing difficulties and can be given to children as young as two.
The world could be free of malaria – one of the oldest and deadliest diseases to affect humanity – within a generation, a major report says. Each year there are still more than 200 million cases of the disease, which mostly kills young children.
The drug-resistant fungus, Candida Auris, was only discovered 10 years ago but is now one of the world’s most feared hospital microbes. There have been outbreaks across the world, and new research shows that global warming may have increased its prevalence...
Researchers say they can accurately identify people on track to develop Alzheimer’s disease before symptoms appear, which could help the progress of drug trials. US scientists were able to use levels of a protein in the blood to help predict its build-up in the brain. Continue reading
NHS GP’s say they are misdiagnosing patients because consultation times are too short.. A survey of family doctors found more than one in three said they had failed to properly diagnose cases because they did not have enough time to fully assess them. Typically, the time slot to see a patient is around 10 minutes. Continue reading